What is the first step toward resolution when corneal epithelial cells suffer trauma?

When corneal epithelial cells experience trauma, the initial response for healing involves the sliding and migrating of adjacent remaining epithelial cells to cover the injured area. This process is crucial because the epithelial layer plays a vital role in protecting the underlying tissues of the cornea and maintaining its integrity.

The migration of neighboring healthy epithelial cells allows for rapid closure of the defect. This response is an essential part of the wound healing process; it helps to restore the barrier function of the cornea and minimizes the risk of infection. The epithelial cells are particularly adept at this migration due to their ability to reorganize and move towards the site of injury in a coordinated manner.

While the other options may play roles in the overall healing process or contribute to the health of the eye, they do not represent the immediate or first response to epithelial trauma. For instance, increased tear film production may help with lubrication and protection after some healing has begun, but it does not address the need for immediate cell replacement at the injury site. Similarly, cell division in the stroma and application of therapeutic lenses may be supportive measures but are not the first steps in the process. The primary focus is on the rapid response of cell migration to quickly restore the epithelial layer.