If a soft contact lens is not properly neutralized, how does the residual hydrogen peroxide affect the cornea?

Residual hydrogen peroxide on soft contact lenses can indeed lead to epithelial damage on the cornea. When hydrogen peroxide comes into contact with the corneal epithelium, it can cause oxidative stress, which may disrupt cell membranes, leading to cell death and inflammation. This reactive nature of hydrogen peroxide, especially when not neutralized, enhances its potential for harm to the delicate cells of the cornea.

The corneal epithelium consists of tightly packed cells that serve as a protective barrier against environmental factors and pathogens. Any disruption to this layer can result in pain, discomfort, and increased susceptibility to infection. Therefore, proper neutralization of hydrogen peroxide is critical to ensure safe wear of contact lenses and to maintain the health of the cornea. The understanding of this mechanism is vital for contact lens practitioners to educate their patients on safe lens care practices.