Dry eyes are a common side effect of which of the following medications?

The selection of oral contraceptives, Accutane, and antihistamines is correct because these medications have well-documented side effects that can lead to dry eyes.

Oral contraceptives can cause hormonal changes that might lead to alterations in tear film composition and function. This can result in a decrease in tear production, contributing to the sensation of dry eyes.

Accutane, also known as isotretinoin, is frequently prescribed for severe acne and is known for its ability to significantly reduce sebaceous gland activity, which includes the glands responsible for producing certain components of the tear film. Therefore, it can lead to a notable decrease in tear production, resulting in dryness.

Antihistamines, commonly used to treat allergic reactions, can also cause dryness in the eyes by blocking histamine receptors that are involved in the lacrimal gland's tear production. This further exacerbates dry eye symptoms, especially in individuals already predisposed to dryness.

The other choices include medications that may not have as strong or direct a correlation with inducing dry eyes as those in the selected option. Therefore, the choice of oral contraceptives, Accutane, and antihistamines as agents that can lead to dry eyes is well-founded based on their known pharmacological